Muscular recovery: the gut-muscle connection

Understanding muscle recovery is key to understanding how AXP Recovery Probiotic can help you improve recovery time and sustain high level training and competition.

When you understand the mechanism behind muscle repair, you can see just how innovative, yet logical, AXP Recovery Probiotic is.

 

EXERCISE-INDUCED MUSCLE DAMAGE

When muscle tissue is repaired following exercise-induced damage, it helps to build muscle mass and condition our body for optimal performance.

While an essential part of training, muscle damage inevitably leads to inflammation which causes muscle soreness and swelling as well as short-term reductions in strength and range of motion.

In athletes, these physical changes can impair subsequent training capacity and performance intensity, especially during intense periods of back-to-back training and competition. 

Many athletes will take non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac, to help manage these symptoms. However, this is like trying to put out the fire after it’s gotten out of control. What’s more, the side effects of their overuse are not pretty.

 

IMMUNE-MEDIATED INFLAMMATION & MUSCLE REMODELLING

What you need to understand is that some inflammation is a necessary response to kickstart muscle repair, so putting it all out isn’t the goal.

When muscle tissue is damaged, the immune system is called in to stimulate an inflammatory response, releasing chemical messengers (inflammatory cytokines) which act to coordinate muscle cells, blood vessels and connective tissue towards rebuilding and repairing muscle.

However, an excessive inflammatory response caused by underlying immune dysfunction can increase symptoms such as muscle soreness, delaying recovery time and disrupting optimal performance due to too many pro-inflammatory cytokines.

Modulating muscle inflammation by addressing underlying immune dysfunction can help to prevent this, and thereby accelerate muscle recovery.

This approach is akin to fire prevention strategies, to stop fires from getting out of control.

So how do we do that?

  

THE GUT MICROBIOTA & IMMUNE-MEDIATED INFLAMMATION

Because the vast majority of the body’s immune cells are found just below the lining of the gut (the large intestine), it is the gateway to immune regulation.

The gut microbiota is the community of living microbes found inside the large intestine, communicating with their immune cell neighbours and telling them what to do. 

They can alter how immune cells function by changing the type of chemical messengers they produce. The immune system can create both pro-inflammatory and anti-inflammatory chemical messengers; the health of your gut microbiome determines how well these two groups are balanced.

A healthy gut microbiome enhances immune system function and keeps systemic inflammation under control by ensuring the correct balance of pro-inflammatory and anti-inflammatory chemical messengers are being produced by immune cells.

 

PROBIOTICS FOR MUSCULAR RECOVERY

Probiotics are live microbes associated with health benefits that can be taken as a supplement. 

Just like resident gut microbes, select probiotic strains have the ability to interact with immune cells and modulate the chemical messengers they produce, often favouring the production of those that are anti-inflammatory.

This effect gets transferred from immune cells living in the gut, to the immune cells that enter muscle tissue to facilitate repair.

Therefore, probiotics have the potential to influence inflammation and muscle remodelling during recovery from exercise by controlling the immune system’s inflammatory response to exercise-induced muscle damage.

However, how effective they are at doing this is extremely strain specific- this means that not all probiotics will work the same or have the same effect.

AXP Recovery Probiotic contains two particular probiotic strains, Bifidobacterium breve BR03 and Streptococcus thermophilus FP4, which are clinically proven to modulate inflammation and improve muscle recovery time.

Our clinical trial helps us to know it will have the beneficial effect we’re looking for, and work as intended.

 

 

Muscular recovery: the gut-muscle connection